Workflow: richCluster Example

load_cluster_data <- function(from_scratch=FALSE) {
  if (!from_scratch) {
    cluster_result <- readRDS(system.file("extdata", "cluster_result.rds", package = "richCluster"))
  } else {
    rr1 <- read.delim(system.file("extdata", "HF36wk_vs_HF12wk.txt", package="richCluster"))
    rr2 <- read.delim(system.file("extdata", "HF36wk_vs_WT12wk.txt", package="richCluster"))
    
    enrichment_results <- list(rr1, rr2)
    rr_names <- c('hf36_vs_hf12', 'wt36_vs_wt12')
    
    cluster_result <- richCluster::cluster(
      enrichment_results, df_names = rr_names, min_terms = 3, min_value=0.0001,
      distance_metric = "kappa", distance_cutoff = 0.5,
      linkage_method = "average", linkage_cutoff = 0.5
    )
  }
  return(cluster_result)
}

cluster_result <- load_cluster_data(from_scratch = FALSE)

c_hmap <- cluster_hmap(cluster_result)
#> Warning in fix_not_all_unique(rownames(x)): Not all the values are unique -
#> manually added prefix numbers
c_hmap

c_bar <- cluster_bar(cluster_result)
c_bar
#> Warning: Ignoring 3 observations

c_dot <- cluster_dot(cluster_result)
c_dot
#> Warning: Ignoring 3 observations
#> Warning: `line.width` does not currently support multiple values.
#> Warning: `line.width` does not currently support multiple values.

clusters <- c("blood vessel development", "response to lipoprotein particle", "positive regulation of cell death")
terms <- c("myelination", "lipid oxidation")

t_hmap <- term_hmap(cluster_result, clusters, terms, value_type = "Padj")
t_hmap

t_bar <- term_bar(cluster_result, 1)
t_bar

t_dot <- term_dot(cluster_result, 1)
t_dot
#> Warning: `line.width` does not currently support multiple values.
#> Warning: `line.width` does not currently support multiple values.

cluster_df <- export_df(cluster_result)
head(cluster_df)
#>   Cluster              ClusterName                                Term
#> 1       1 blood vessel development            blood vessel development
#> 2       1 blood vessel development   cardiovascular system development
#> 3       1 blood vessel development             vasculature development
#> 4       2 sterol metabolic process       cholesterol metabolic process
#> 5       2 sterol metabolic process secondary alcohol metabolic process
#> 6       2 sterol metabolic process            sterol metabolic process
#>   Annot_hf36_vs_hf12 Annotated_hf36_vs_hf12 Significant_hf36_vs_hf12
#> 1         GO:0001568                    634                      106
#> 2         GO:0072358                    677                      109
#> 3         GO:0001944                    663                      109
#> 4         GO:0008203                    114                       37
#> 5         GO:1902652                    118                       37
#> 6         GO:0016125                    124                       39
#>   Pvalue_hf36_vs_hf12 Padj_hf36_vs_hf12
#> 1        4.878788e-17      2.655627e-15
#> 2        2.716755e-16      1.345862e-14
#> 3        5.960167e-17      3.166069e-15
#> 4        9.677181e-16      4.467717e-14
#> 5        3.381284e-15      1.490808e-13
#> 6        5.421669e-16      2.542993e-14
#>                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   GeneID_hf36_vs_hf12
#> 1                 Slit2,Ctgf,Tcf7l2,Anxa2,Mmp19,Col1a2,Fap,Nr4a1,Jak1,Pdgfa,Angptl4,Spi1,Mfge8,Wnt5a,Lep,Pde2a,Arhgap24,C3ar1,Aldh1a2,Tgfa,Pdgfrb,Rgcc,Lox,Itgb1bp1,C6,Pf4,Enpep,Thy1,Lrg1,Stab1,Acvr2b,Tnfaip2,Ecscr,Ccl11,Serpine1,Fzd5,Parva,Syk,Cd36,Adam8,Bmper,Tnfrsf1a,Ndst1,Jun,Fgf1,Shh,Ccm2,Arid2,Nsdhl,Ephb2,Gpi1,Cd34,Itgb2,Gpld1,Xbp1,Cxcl12,Atp5b,Cela1,Emp2,Ntrk2,Ddah1,Anpep,Adam15,Apoe,Runx1,Hpgd,Pik3cb,Col8a2,Sparc,C5ar1,Gpc3,Ptger4,Hif3a,Vav3,Tbxa2r,Thbs1,Lrp5,Bmp7,Ptk2b,Hspb1,Jam3,Gpx1,Notch2,Cybb,Ccl2,Ccr2,Serpinf1,Lgals3,Myh9,Egln1,Pik3r6,Ppp1r16b,Mmp9,Qk,Srpx2,Ncoa6,Sema5a,Itgav,Htatip2,Cib1,Sema4a,Ctsh,Hdac9,Cdh2,Enpp2,Rapgef3
#> 2 Slit2,Ctgf,Tcf7l2,Anxa2,Mmp19,Col1a2,Fap,Nr4a1,Jak1,Pdgfa,Angptl4,Spi1,Mfge8,Wnt5a,Lep,Pde2a,Arhgap24,C3ar1,Aldh1a2,Tgfa,Pdgfrb,Rgcc,Lox,Sgcb,Itgb1bp1,C6,Pf4,Enpep,Thy1,Lrg1,Stab1,Acvr2b,Tnfaip2,Ecscr,Ccl11,Serpine1,Fzd5,Parva,Syk,Cd36,Adam8,Bmper,Tnfrsf1a,Ndst1,Jun,Fgf1,Shh,Ccm2,Arid2,Nsdhl,Ephb2,Gpi1,Cd34,Itgb2,Gpld1,Xbp1,Cxcl12,Atp5b,Cela1,Emp2,Ntrk2,Prox2,Ddah1,Anpep,Adam15,Apoe,Runx1,Hpgd,Pik3cb,Col8a2,Sparc,C5ar1,Gpc3,Ptger4,Hif3a,Vav3,Tbxa2r,Thbs1,Lrp5,Bmp7,Ptk2b,Hspb1,Jam3,Gpx1,Notch2,Cybb,Ccl2,Ccr2,Serpinf1,Lgals3,Myh9,Egln1,Pik3r6,Ppp1r16b,Mmp9,Qk,Igf1,Srpx2,Ncoa6,Sema5a,Itgav,Htatip2,Cib1,Sema4a,Ctsh,Hdac9,Cdh2,Enpp2,Rapgef3
#> 3 Slit2,Ctgf,Tcf7l2,Anxa2,Mmp19,Col1a2,Fap,Nr4a1,Jak1,Pdgfa,Angptl4,Spi1,Mfge8,Wnt5a,Lep,Pde2a,Arhgap24,C3ar1,Aldh1a2,Tgfa,Pdgfrb,Rgcc,Lox,Sgcb,Itgb1bp1,C6,Pf4,Enpep,Thy1,Lrg1,Stab1,Acvr2b,Tnfaip2,Ecscr,Ccl11,Serpine1,Fzd5,Parva,Syk,Cd36,Adam8,Bmper,Tnfrsf1a,Ndst1,Jun,Fgf1,Shh,Ccm2,Arid2,Nsdhl,Ephb2,Gpi1,Cd34,Itgb2,Gpld1,Xbp1,Cxcl12,Atp5b,Cela1,Emp2,Ntrk2,Prox2,Ddah1,Anpep,Adam15,Apoe,Runx1,Hpgd,Pik3cb,Col8a2,Sparc,C5ar1,Gpc3,Ptger4,Hif3a,Vav3,Tbxa2r,Thbs1,Lrp5,Bmp7,Ptk2b,Hspb1,Jam3,Gpx1,Notch2,Cybb,Ccl2,Ccr2,Serpinf1,Lgals3,Myh9,Egln1,Pik3r6,Ppp1r16b,Mmp9,Qk,Igf1,Srpx2,Ncoa6,Sema5a,Itgav,Htatip2,Cib1,Sema4a,Ctsh,Hdac9,Cdh2,Enpp2,Rapgef3
#> 4                                                                                                                                                                                                                                                                                                                                                                                                                                               Hdlbp,Acadvl,Dhcr24,Ephx2,Insig1,Tm7sf2,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Insig2,Fgf1,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Srebf1,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Lrp5,Srebf2,Vldlr,Hmgcr,Abca2,Mvk,Hmgcs1,Cln8,Sqle,G6pdx,Scp2
#> 5                                                                                                                                                                                                                                                                                                                                                                                                                                               Hdlbp,Acadvl,Dhcr24,Ephx2,Insig1,Tm7sf2,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Insig2,Fgf1,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Srebf1,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Lrp5,Srebf2,Vldlr,Hmgcr,Abca2,Mvk,Hmgcs1,Cln8,Sqle,G6pdx,Scp2
#> 6                                                                                                                                                                                                                                                                                                                                                                                                                                     Hdlbp,Acadvl,Dhcr24,Ephx2,Insig1,Tm7sf2,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Insig2,Fgf1,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Srebf1,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Lrp5,Srebf2,Vldlr,Hmgcr,Lbr,Abca2,Mvk,Hmgcs1,Cln8,Sqle,G6pdx,Scp2,Msmo1
#>   Annot_wt36_vs_wt12 Annotated_wt36_vs_wt12 Significant_wt36_vs_wt12
#> 1         GO:0001568                    634                       67
#> 2         GO:0072358                    677                       70
#> 3         GO:0001944                    663                       69
#> 4         GO:0008203                    114                       30
#> 5         GO:1902652                    118                       30
#> 6         GO:0016125                    124                       32
#>   Pvalue_wt36_vs_wt12 Padj_wt36_vs_wt12
#> 1        8.139403e-09      3.156836e-07
#> 2        9.222440e-09      3.504990e-07
#> 3        9.065615e-09      3.462790e-07
#> 4        3.831384e-14      3.863568e-12
#> 5        1.038092e-13      9.813860e-12
#> 6        9.917374e-15      1.136441e-12
#>                                                                                                                                                                                                                                                                                                                                                                                                        GeneID_wt36_vs_wt12
#> 1                  Slit2,Ctgf,Tcf7l2,Anxa2,Col1a2,Nr4a1,Pdgfa,Angptl4,Mfge8,Lep,Pde2a,Arhgap24,C3ar1,Pdgfrb,Lox,Plxdc1,C6,Pf4,Thy1,Col1a1,Serpine1,Ddit3,Pknox1,Syk,Cd36,Adam8,Ndst1,Jun,Nsdhl,Itgb2,Ccl5,Xbp1,Cxcl12,Cela1,Emp2,Ntrk2,Ddah1,Ephb3,Btg1,Apoe,Hpgd,Pik3cb,Sparc,C5ar1,Hif3a,Smo,Vav3,Plxnd1,Ptk2b,Hspb1,Notch2,Gpx1,Cybb,Ets1,Ccr2,Lgals3,Setd2,Vezf1,Adm,Reck,Ppp1r16b,Qk,Srpx2,Sema5a,Htatip2,Unc5b,Hdac9
#> 2 Slit2,Ctgf,Tcf7l2,Anxa2,Col1a2,Nr4a1,Pdgfa,Angptl4,Mfge8,Lep,Pde2a,Arhgap24,C3ar1,Pdgfrb,Lox,Plxdc1,C6,Pf4,Thy1,Col1a1,Serpine1,Ddit3,Pknox1,Syk,Cd36,Adam8,Ndst1,Jun,Nxn,Nsdhl,Itgb2,Ccl5,Xbp1,Cxcl12,Cela1,Emp2,Ntrk2,Prox2,Ddah1,Ephb3,Btg1,Apoe,Hpgd,Pik3cb,Sparc,C5ar1,Hif3a,Smo,Errfi1,Vav3,Plxnd1,Ptk2b,Hspb1,Notch2,Gpx1,Cybb,Ets1,Ccr2,Lgals3,Setd2,Vezf1,Adm,Reck,Ppp1r16b,Qk,Srpx2,Sema5a,Htatip2,Unc5b,Hdac9
#> 3     Slit2,Ctgf,Tcf7l2,Anxa2,Col1a2,Nr4a1,Pdgfa,Angptl4,Mfge8,Lep,Pde2a,Arhgap24,C3ar1,Pdgfrb,Lox,Plxdc1,C6,Pf4,Thy1,Col1a1,Serpine1,Ddit3,Pknox1,Syk,Cd36,Adam8,Ndst1,Jun,Nsdhl,Itgb2,Ccl5,Xbp1,Cxcl12,Cela1,Emp2,Ntrk2,Prox2,Ddah1,Ephb3,Btg1,Apoe,Hpgd,Pik3cb,Sparc,C5ar1,Hif3a,Smo,Errfi1,Vav3,Plxnd1,Ptk2b,Hspb1,Notch2,Gpx1,Cybb,Ets1,Ccr2,Lgals3,Setd2,Vezf1,Adm,Reck,Ppp1r16b,Qk,Srpx2,Sema5a,Htatip2,Unc5b,Hdac9
#> 4                                                                                                                                                                                                                                             Dhcr24,Insig1,Tm7sf2,Pon1,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Hmgcs2,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Srebf2,Aplp2,Hmgcr,Abca2,Mvk,Hmgcs1,Sqle,G6pdx
#> 5                                                                                                                                                                                                                                             Dhcr24,Insig1,Tm7sf2,Pon1,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Hmgcs2,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Srebf2,Aplp2,Hmgcr,Abca2,Mvk,Hmgcs1,Sqle,G6pdx
#> 6                                                                                                                                                                                                                                  Dhcr24,Insig1,Tm7sf2,Pon1,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Hmgcs2,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Srebf2,Aplp2,Hmgcr,Abca2,Mvk,Lipa,Hmgcs1,Sqle,G6pdx,Msmo1
#>                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                         GeneID
#> 1                                  Slit2,Ctgf,Tcf7l2,Anxa2,Mmp19,Col1a2,Fap,Nr4a1,Jak1,Pdgfa,Angptl4,Spi1,Mfge8,Wnt5a,Lep,Pde2a,Arhgap24,C3ar1,Aldh1a2,Tgfa,Pdgfrb,Rgcc,Lox,Itgb1bp1,C6,Pf4,Enpep,Thy1,Lrg1,Stab1,Acvr2b,Tnfaip2,Ecscr,Ccl11,Serpine1,Fzd5,Parva,Syk,Cd36,Adam8,Bmper,Tnfrsf1a,Ndst1,Jun,Fgf1,Shh,Ccm2,Arid2,Nsdhl,Ephb2,Gpi1,Cd34,Itgb2,Gpld1,Xbp1,Cxcl12,Atp5b,Cela1,Emp2,Ntrk2,Ddah1,Anpep,Adam15,Apoe,Runx1,Hpgd,Pik3cb,Col8a2,Sparc,C5ar1,Gpc3,Ptger4,Hif3a,Vav3,Tbxa2r,Thbs1,Lrp5,Bmp7,Ptk2b,Hspb1,Jam3,Gpx1,Notch2,Cybb,Ccl2,Ccr2,Serpinf1,Lgals3,Myh9,Egln1,Pik3r6,Ppp1r16b,Mmp9,Qk,Srpx2,Ncoa6,Sema5a,Itgav,Htatip2,Cib1,Sema4a,Ctsh,Hdac9,Cdh2,Enpp2,Rapgef3,Slit2,Ctgf,Tcf7l2,Anxa2,Col1a2,Nr4a1,Pdgfa,Angptl4,Mfge8,Lep,Pde2a,Arhgap24,C3ar1,Pdgfrb,Lox,Plxdc1,C6,Pf4,Thy1,Col1a1,Serpine1,Ddit3,Pknox1,Syk,Cd36,Adam8,Ndst1,Jun,Nsdhl,Itgb2,Ccl5,Xbp1,Cxcl12,Cela1,Emp2,Ntrk2,Ddah1,Ephb3,Btg1,Apoe,Hpgd,Pik3cb,Sparc,C5ar1,Hif3a,Smo,Vav3,Plxnd1,Ptk2b,Hspb1,Notch2,Gpx1,Cybb,Ets1,Ccr2,Lgals3,Setd2,Vezf1,Adm,Reck,Ppp1r16b,Qk,Srpx2,Sema5a,Htatip2,Unc5b,Hdac9
#> 2 Slit2,Ctgf,Tcf7l2,Anxa2,Mmp19,Col1a2,Fap,Nr4a1,Jak1,Pdgfa,Angptl4,Spi1,Mfge8,Wnt5a,Lep,Pde2a,Arhgap24,C3ar1,Aldh1a2,Tgfa,Pdgfrb,Rgcc,Lox,Sgcb,Itgb1bp1,C6,Pf4,Enpep,Thy1,Lrg1,Stab1,Acvr2b,Tnfaip2,Ecscr,Ccl11,Serpine1,Fzd5,Parva,Syk,Cd36,Adam8,Bmper,Tnfrsf1a,Ndst1,Jun,Fgf1,Shh,Ccm2,Arid2,Nsdhl,Ephb2,Gpi1,Cd34,Itgb2,Gpld1,Xbp1,Cxcl12,Atp5b,Cela1,Emp2,Ntrk2,Prox2,Ddah1,Anpep,Adam15,Apoe,Runx1,Hpgd,Pik3cb,Col8a2,Sparc,C5ar1,Gpc3,Ptger4,Hif3a,Vav3,Tbxa2r,Thbs1,Lrp5,Bmp7,Ptk2b,Hspb1,Jam3,Gpx1,Notch2,Cybb,Ccl2,Ccr2,Serpinf1,Lgals3,Myh9,Egln1,Pik3r6,Ppp1r16b,Mmp9,Qk,Igf1,Srpx2,Ncoa6,Sema5a,Itgav,Htatip2,Cib1,Sema4a,Ctsh,Hdac9,Cdh2,Enpp2,Rapgef3,Slit2,Ctgf,Tcf7l2,Anxa2,Col1a2,Nr4a1,Pdgfa,Angptl4,Mfge8,Lep,Pde2a,Arhgap24,C3ar1,Pdgfrb,Lox,Plxdc1,C6,Pf4,Thy1,Col1a1,Serpine1,Ddit3,Pknox1,Syk,Cd36,Adam8,Ndst1,Jun,Nxn,Nsdhl,Itgb2,Ccl5,Xbp1,Cxcl12,Cela1,Emp2,Ntrk2,Prox2,Ddah1,Ephb3,Btg1,Apoe,Hpgd,Pik3cb,Sparc,C5ar1,Hif3a,Smo,Errfi1,Vav3,Plxnd1,Ptk2b,Hspb1,Notch2,Gpx1,Cybb,Ets1,Ccr2,Lgals3,Setd2,Vezf1,Adm,Reck,Ppp1r16b,Qk,Srpx2,Sema5a,Htatip2,Unc5b,Hdac9
#> 3     Slit2,Ctgf,Tcf7l2,Anxa2,Mmp19,Col1a2,Fap,Nr4a1,Jak1,Pdgfa,Angptl4,Spi1,Mfge8,Wnt5a,Lep,Pde2a,Arhgap24,C3ar1,Aldh1a2,Tgfa,Pdgfrb,Rgcc,Lox,Sgcb,Itgb1bp1,C6,Pf4,Enpep,Thy1,Lrg1,Stab1,Acvr2b,Tnfaip2,Ecscr,Ccl11,Serpine1,Fzd5,Parva,Syk,Cd36,Adam8,Bmper,Tnfrsf1a,Ndst1,Jun,Fgf1,Shh,Ccm2,Arid2,Nsdhl,Ephb2,Gpi1,Cd34,Itgb2,Gpld1,Xbp1,Cxcl12,Atp5b,Cela1,Emp2,Ntrk2,Prox2,Ddah1,Anpep,Adam15,Apoe,Runx1,Hpgd,Pik3cb,Col8a2,Sparc,C5ar1,Gpc3,Ptger4,Hif3a,Vav3,Tbxa2r,Thbs1,Lrp5,Bmp7,Ptk2b,Hspb1,Jam3,Gpx1,Notch2,Cybb,Ccl2,Ccr2,Serpinf1,Lgals3,Myh9,Egln1,Pik3r6,Ppp1r16b,Mmp9,Qk,Igf1,Srpx2,Ncoa6,Sema5a,Itgav,Htatip2,Cib1,Sema4a,Ctsh,Hdac9,Cdh2,Enpp2,Rapgef3,Slit2,Ctgf,Tcf7l2,Anxa2,Col1a2,Nr4a1,Pdgfa,Angptl4,Mfge8,Lep,Pde2a,Arhgap24,C3ar1,Pdgfrb,Lox,Plxdc1,C6,Pf4,Thy1,Col1a1,Serpine1,Ddit3,Pknox1,Syk,Cd36,Adam8,Ndst1,Jun,Nsdhl,Itgb2,Ccl5,Xbp1,Cxcl12,Cela1,Emp2,Ntrk2,Prox2,Ddah1,Ephb3,Btg1,Apoe,Hpgd,Pik3cb,Sparc,C5ar1,Hif3a,Smo,Errfi1,Vav3,Plxnd1,Ptk2b,Hspb1,Notch2,Gpx1,Cybb,Ets1,Ccr2,Lgals3,Setd2,Vezf1,Adm,Reck,Ppp1r16b,Qk,Srpx2,Sema5a,Htatip2,Unc5b,Hdac9
#> 4                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           Hdlbp,Acadvl,Dhcr24,Ephx2,Insig1,Tm7sf2,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Insig2,Fgf1,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Srebf1,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Lrp5,Srebf2,Vldlr,Hmgcr,Abca2,Mvk,Hmgcs1,Cln8,Sqle,G6pdx,Scp2,Dhcr24,Insig1,Tm7sf2,Pon1,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Hmgcs2,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Srebf2,Aplp2,Hmgcr,Abca2,Mvk,Hmgcs1,Sqle,G6pdx
#> 5                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                           Hdlbp,Acadvl,Dhcr24,Ephx2,Insig1,Tm7sf2,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Insig2,Fgf1,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Srebf1,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Lrp5,Srebf2,Vldlr,Hmgcr,Abca2,Mvk,Hmgcs1,Cln8,Sqle,G6pdx,Scp2,Dhcr24,Insig1,Tm7sf2,Pon1,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Hmgcs2,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Srebf2,Aplp2,Hmgcr,Abca2,Mvk,Hmgcs1,Sqle,G6pdx
#> 6                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                      Hdlbp,Acadvl,Dhcr24,Ephx2,Insig1,Tm7sf2,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Insig2,Fgf1,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Srebf1,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Lrp5,Srebf2,Vldlr,Hmgcr,Lbr,Abca2,Mvk,Hmgcs1,Cln8,Sqle,G6pdx,Scp2,Msmo1,Dhcr24,Insig1,Tm7sf2,Pon1,Lep,Cyp51,Sc5d,Dgat2,Ldlr,Fdps,Mvd,Lss,Nsdhl,Fdft1,Hsd17b7,Hmgcs2,Acadl,Abca1,Apoe,Mbtps1,Npc2,Pmvk,Srebf2,Aplp2,Hmgcr,Abca2,Mvk,Lipa,Hmgcs1,Sqle,G6pdx,Msmo1
#>         Pvalue         Padj
#> 1 4.069702e-09 1.578418e-07
#> 2 4.611220e-09 1.752495e-07
#> 3 4.532808e-09 1.731395e-07
#> 4 1.964078e-14 1.954122e-12
#> 5 5.359523e-14 4.981471e-12
#> 6 5.229770e-15 5.809354e-13