escalation 0.2.3
- Added three new vignettes on phase I/II designs, TITE-designs, and
combination designs.
- Added BOIN-COMB MTD selector
- Added tests and docs
- Fixed bugs and typos
escalation 0.2.2
- Added boin12_rds() to tabulate desirability scores in a BOIN12
trial.
escalation 0.2.1
- Added unadmit_untested(), a selector to explicitly mark any untested
and non-recomended dose as inadmissible via dose_admissible().
escalation 0.2.0
- Added support for treatment combinations by allowing dose to become
a vector of indices rather than a scalar.
- Added BOIN COMB design for treatment combinations.
escalation 0.1.10
escalation 0.1.9
- Fixed inheritance problems with as_tibble, summary and print
dose_selector generics
- Added many tests of dose_selector consistency.
escalation 0.1.8
- Made tests faster for CRAN
escalation 0.1.7
- Added ability to import and export PatientSamples
- Split the simulation vignette
escalation 0.1.6
- Implement efficient simulation comparison method of Sweeting et
al. in simulate_compare()
- Implement BOIN12 design
- Add MTD / OBD selectors for TPI, mTPI, mTPI2 and BOIN12 for final
dose choice at end of a trial
escalation 0.1.5
- Add mTPI2 dose-finding method
- Fixed some bugs
escalation 0.1.4
- Added Neuenschwander, Branson & Sponer’s method for phase
I.
- Added Ji et al.’s TPI & mTI methods for phase I.
- Added Thall & Cook’s EffTox method for phase I/II.
- Added Wages & Tait’s method for phase I/II.
escalation 0.1.3
- Mainly small changes to comply with dplyr v1.0.
- simulations and crystallised_dose_paths given summary method
- NOTE squash
escalation 0.1.2
- Methods for simulation and calculating dose-paths added.
- A bit more on the general selector interface.
- Everything new has tests, and more tests on old stuff.
escalation 0.1.1
- Initial release.
- dfcrm, BOIN, 3+3 models supported.
- several objects included to facilitate stopping at different
events.
- class for a fixed escalation plan included, as sometimes used with
CRM.