cytometree: Automated Cytometry Gating and Annotation
Given the hypothesis of a bi-modal distribution of cells for
    each marker, the algorithm constructs a binary tree, the nodes of which are
    subpopulations of cells. At each node, observed cells and markers are modeled
    by both a family of normal distributions and a family of bi-modal normal mixture
    distributions. Splitting is done according to a normalized difference of AIC
    between the two families. Method is detailed in: Commenges, Alkhassim, Gottardo, 
    Hejblum & Thiebaut (2018) <doi:10.1002/cyto.a.23601>. 
| Version: | 
2.0.6 | 
| Depends: | 
R (≥ 3.1.0), Rcpp (≥ 0.12.11) | 
| Imports: | 
ggplot2, graphics, igraph, mclust, methods, stats, cowplot, GoFKernel | 
| LinkingTo: | 
Rcpp, RcppArmadillo | 
| Suggests: | 
knitr, formatR, rmarkdown, viridis, testthat | 
| Published: | 
2025-07-24 | 
| DOI: | 
10.32614/CRAN.package.cytometree | 
| Author: | 
Chariff Alkhassim [aut],
  Boris P Hejblum [cre, aut],
  Anthony Devaux [aut],
  Van Hung Huynh Tran [aut],
  Melany Durand [aut] | 
| Maintainer: | 
Boris P Hejblum  <boris.hejblum at u-bordeaux.fr> | 
| BugReports: | 
https://github.com/sistm/Cytometree/issues | 
| License: | 
LGPL-3 | file LICENSE | 
| URL: | 
https://sistm.github.io/cytometree/,
https://github.com/sistm/Cytometree/ | 
| NeedsCompilation: | 
yes | 
| Citation: | 
cytometree citation info  | 
| Materials: | 
README, NEWS  | 
| CRAN checks: | 
cytometree results | 
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