TrialEmulation: Causal Analysis of Observational Time-to-Event Data

Implements target trial emulation methods to apply randomized clinical trial design and analysis in an observational setting. Using marginal structural models, it can estimate intention-to-treat and per-protocol effects in emulated trials using electronic health records. A description and application of the method can be found in Danaei et al (2013) <doi:10.1177/0962280211403603>.

Version: 0.0.3.9
Depends: R (≥ 3.5.0)
Imports: Rcpp, broom (≥ 0.7.10), checkmate, data.table (≥ 1.9.8), formula.tools, mvtnorm, parglm, sandwich
LinkingTo: Rcpp
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0), withr
Published: 2024-09-09
DOI: 10.32614/CRAN.package.TrialEmulation
Author: Roonak Rezvani ORCID iD [aut] (Original package author), Isaac Gravestock ORCID iD [aut, cre], Li Su [aut], Medical Research Council (MRC) [fnd], F. Hoffmann-La Roche AG [cph, fnd]
Maintainer: Isaac Gravestock <isaac.gravestock at roche.com>
BugReports: https://github.com/Causal-LDA/TrialEmulation/issues
License: Apache License (≥ 2)
URL: https://causal-lda.github.io/TrialEmulation/, https://github.com/Causal-LDA/TrialEmulation
NeedsCompilation: yes
Language: en-GB
Materials: README NEWS
CRAN checks: TrialEmulation results

Documentation:

Reference manual: TrialEmulation.pdf
Vignettes: Getting-Started (source, R code)

Downloads:

Package source: TrialEmulation_0.0.3.9.tar.gz
Windows binaries: r-devel: TrialEmulation_0.0.3.9.zip, r-release: TrialEmulation_0.0.3.9.zip, r-oldrel: TrialEmulation_0.0.3.9.zip
macOS binaries: r-release (arm64): TrialEmulation_0.0.3.9.tgz, r-oldrel (arm64): TrialEmulation_0.0.3.9.tgz, r-release (x86_64): TrialEmulation_0.0.3.9.tgz, r-oldrel (x86_64): TrialEmulation_0.0.3.9.tgz
Old sources: TrialEmulation archive

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