SCORPION: Single Cell Oriented Reconstruction of PANDA Individually Optimized Networks

Constructs cell-type–specific gene regulatory networks from single-cell RNA-sequencing data. The method implements the SCORPION algorithm, which first aggregates individual cells into super-cells and then applies PANDA (Passing Attributes between Networks for Data Assimilation) to infer transcription factor–target regulatory relationships. It also provides statistical methods for differential edge analysis.

Version:	1.3.2
Depends:	R (≥ 3.5.0)
Imports:	cli, methods, irlba, igraph, RANN, Matrix, pbapply, dplyr, furrr, future
Suggests:	RhpcBLASctl, testthat
Published:	2026-03-10
DOI:	10.32614/CRAN.package.SCORPION
Author:	Daniel Osorio [aut, cre], Marieke L. Kuijjer [aut]
Maintainer:	Daniel Osorio <daniecos at uio.no>
BugReports:	https://github.com/kuijjerlab/SCORPION/issues
License:	GPL-3
URL:	https://github.com/kuijjerlab/SCORPION
NeedsCompilation:	no
CRAN checks:	SCORPION results

Documentation:

Reference manual:

SCORPION.html , SCORPION.pdf

Downloads:

Package source:	SCORPION_1.3.2.tar.gz
Windows binaries:	r-devel: SCORPION_1.3.2.zip, r-release: SCORPION_1.3.2.zip, r-oldrel: SCORPION_1.3.2.zip
macOS binaries:	r-release (arm64): SCORPION_1.3.2.tgz, r-oldrel (arm64): SCORPION_1.3.2.tgz, r-release (x86_64): SCORPION_1.3.2.tgz, r-oldrel (x86_64): SCORPION_1.3.2.tgz
Old sources:	SCORPION archive

Linking:

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