A systematic biology tool was developed to identify dysregulated miRNAs via a miRNA-miRNA interaction network. 'IDMIR' first constructed a weighted miRNA interaction network through integrating miRNA-target interaction information, molecular function data from Gene Ontology (GO) database and gene transcriptomic data in specific-disease context, and then, it used a network propagation algorithm on the network to identify significantly dysregulated miRNAs.
| Version: | 0.1.0 |
| Depends: | R (≥ 2.10) |
| Imports: | egg, fastmatch, forestplot, ggplot2, grDevices, grid, igraph, pheatmap, survival, survminer |
| Suggests: | knitr, rmarkdown |
| Published: | 2023-11-09 |
| DOI: | 10.32614/CRAN.package.IDMIR |
| Author: | Junwei Han [aut, cre, cph], Xilong Zhao [aut], Jiashuo Wu [aut] |
| Maintainer: | Junwei Han <hanjunwei1981 at 163.com> |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: | no |
| CRAN checks: | IDMIR results |
| Reference manual: | IDMIR.pdf |
| Vignettes: |
IDMIR User Guide (source, R code) |
| Package source: | IDMIR_0.1.0.tar.gz |
| Windows binaries: | r-devel: IDMIR_0.1.0.zip, r-release: IDMIR_0.1.0.zip, r-oldrel: IDMIR_0.1.0.zip |
| macOS binaries: | r-devel (arm64): IDMIR_0.1.0.tgz, r-release (arm64): IDMIR_0.1.0.tgz, r-oldrel (arm64): IDMIR_0.1.0.tgz, r-devel (x86_64): IDMIR_0.1.0.tgz, r-release (x86_64): IDMIR_0.1.0.tgz, r-oldrel (x86_64): IDMIR_0.1.0.tgz |
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