FIND: Objective Comparison of Phase I Dose-Finding Designs

Generate decision tables and simulate operating characteristics for phase I dose-finding designs to enable objective comparison across methods. Supported designs include the traditional 3+3, Bayesian Optimal Interval (BOIN) (Liu and Yuan (2015) <doi:10.1158/1078-0432.CCR-14-1526>), modified Toxicity Probability Interval-2 (mTPI-2) (Guo et al. (2017) <doi:10.1002/sim.7185>), interval 3+3 (i3+3) (Liu et al. (2020) <doi:10.1177/0962280220939123>), and Generalized 3+3 (G3). Provides visualization tools for comparing decision rules and operating characteristics across multiple designs simultaneously.

Version: 0.1.1
Imports: ggplot2, grid, gridExtra, gtable, dplyr, rlang, stats
Suggests: knitr, rmarkdown, testthat (≥ 3.0.0)
Published: 2025-12-15
DOI: 10.32614/CRAN.package.FIND (may not be active yet)
Author: Yuan Ji [aut], Yunxuan Zhang [aut, cre]
Maintainer: Yunxuan Zhang <yunxuanz at uchicago.edu>
License: MIT + file LICENSE
NeedsCompilation: no
Language: en-US
Materials: NEWS
CRAN checks: FIND results

Documentation:

Reference manual: FIND.html , FIND.pdf
Vignettes: FIND Package Guidance (source, R code)

Downloads:

Package source: FIND_0.1.1.tar.gz
Windows binaries: r-devel: not available, r-release: not available, r-oldrel: not available
macOS binaries: r-release (arm64): FIND_0.1.1.tgz, r-oldrel (arm64): FIND_0.1.1.tgz, r-release (x86_64): FIND_0.1.1.tgz, r-oldrel (x86_64): FIND_0.1.1.tgz

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