Package: simml
Type: Package
Title: Single-Index Models with Multiple-Links
Version: 0.3.1
Maintainer: Hyung Park <parkh15@nyu.edu>
Description: A major challenge in estimating treatment decision rules from a randomized clinical trial dataset with covariates measured at baseline lies in detecting relatively small treatment effect modification-related variability (i.e., the treatment-by-covariates interaction effects on treatment outcomes) against a relatively large non-treatment-related variability (i.e., the main effects of covariates on treatment outcomes). The class of Single-Index Models with Multiple-Links is a novel single-index model specifically designed to estimate a single-index (a linear combination) of the covariates associated with the treatment effect modification-related variability, while allowing a nonlinear association with the treatment outcomes via flexible link functions. The models provide a flexible regression approach to developing treatment decision rules based on patients' data measured at baseline. We refer to Park, Petkova, Tarpey, and Ogden (2020) <doi:10.1016/j.jspi.2019.05.008> and Park, Petkova, Tarpey, and Ogden (2020) <doi:10.1111/biom.13320> (that allows an unspecified X main effect) for detail of the method. The main function of this package is simml().
License: GPL-3
Imports: mgcv
Encoding: UTF-8
RoxygenNote: 6.1.1
NeedsCompilation: no
Authors@R: c(
    person(given = "Hyung", family = "Park",
           role = c("aut", "cre"), email = "parkh15@nyu.edu"),
    person(given = "Eva", family = "Petkova", role = "aut"),
    person(given = "Thaddeus", family = "Tarpey", role = "aut"),
    person(given = c("R.", "Todd"), family = "Ogden", role = "aut"))
Packaged: 2026-11-06 21:26:45 UTC; hyung
Author: Hyung Park [aut, cre],
  Eva Petkova [aut],
  Thaddeus Tarpey [aut],
  R. Todd Ogden [aut]
Repository: CRAN
Date/Publication: 2026-11-06 22:10:02 UTC
