| APrioriPwr | _A Priori_ Synergy Power Analysis Based on Variability and Drug Effect |
| CookDistance | Cook's distance for the coefficient estimates |
| getRTV | Helper function to calculate the relative tumor volume from an imput data frame of tumor growth |
| grwth_data | Example Tumor Growth Data |
| lmmModel | Linear Mixed Effect Model for Tumor Growth |
| lmmModel_estimates | Get estimates from a linear mixed model of tumor growth data |
| lmmSynergy | Synergy calculation using linear-mixed models |
| logLikSubjectDisplacements | Likelihood displacements for the model |
| ObsvsPred | Observed vs predicted values and performance of the model |
| plot_lmmModel | Plotting of tumor growth data from a fitted model |
| plot_lmmSynergy | Plotting synergy results |
| plot_ObsvsPred | Plots of Observed vs Predicted Values |
| plot_ranefDiagnostics | Plots for random effects diagnostics |
| plot_residDiagnostics | Plots for residuals diagnostics |
| plot_SynergyLMM | Plotting SynergyLMM results |
| PostHocPwr | Post hoc power calculation based on simulations of the synergy evaluation using LMM. |
| Pwr | Calculates power based on a model fit |
| Pwr.lme | Performs power calculations |
| PwrSampleSize | _A Priori_ Synergy Power Analysis Based on Sample Size |
| PwrTime | _A Priori_ Synergy Power Analysis Based on Time |
| ranefDiagnostics | Diagnostics of random effects of the linear mixed model |
| residDiagnostics | Diagnostics of residuals of the linear mixed model |
| simulateTumorGrowth | Helper function to simulate tumor growth data for a two-drug combination experiment. |