Exact Sequential Analysis for Poisson and Binomial Data

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Documentation for package ‘Sequential’ version 4.3.4

• DESCRIPTION file.

Help Pages

Sequential-package	Analysis Support, Critical Values, Power, Time to Signal and Sample Size for Sequential Analysis with Poisson and Binomial Data.
Analyze.Binomial	Function for group sequential analyses for binomial data, without the need to know group sizes a priori.
Analyze.CondPoisson	Function to conduct group sequential analyses for conditional Poisson data without the need to know group sizes a priori.
Analyze.Poisson	Function to conduct group sequential analyses for Poisson data without the need to know group sizes a priori.
Analyze.wBinomial	Function for group sequential analyses of multiple weighted binomial endpoints, without the need to know group sizes a priori.
AnalyzeSetUp.Binomial	Function to set up input parameters before using the 'Analyze.Binomial' function for the first time.
AnalyzeSetUp.CondPoisson	Function to set up input parameters before using the 'Analyze.CondPoisson' function for the first time.
AnalyzeSetUp.Poisson	Function to set up input parameters before using the 'Analyze.Poisson' function for the first time.
AnalyzeSetUp.wBinomial	Function to set up input parameters before using the 'Analyze.wBinomial' function for the first time.
ConfidenceInterval.Binomial	Confidence Interval for the Relative Risk Following a Sequential Test with Binary Data.
CV.Binomial	Calculates exact critical values for group and continuous sequential analysis with binomial data.
CV.CondPoisson	Critical values for continuous sequential CMaxSPRT for Poisson data with limited information from historical cohort.
CV.Poisson	Critical values for group and continuous sequential analysis with Poisson data.
Optimal.Binomial	Optimal alpha spending for minimizing expected time to signal for continuous and group sequential analysis with binomial data.
Performance.AlphaSpend.Binomial	Calculates performance and signaling threshold for user-defined alpha spending for sequential analysis with binomial data.
Performance.AlphaSpend.CondPoisson	Calculates performance and signaling thresholds for user-defined alpha spending for sequential analysis with conditional Poisson data.
Performance.AlphaSpend.Poisson	Calculates performance and signaling thresholds for user-defined alpha spending for sequential analysis with Poisson data.
Performance.Binomial	Statistical power, expected time to signal and expected sample size for group and continuous sequential analysis with binomial data.
Performance.CondPoisson	Statistical power, expected time to signal and expected sample size for the continuous sequential CMaxSPRT for Poisson data with limited information from historical cohort.
Performance.Poisson	Calculates statistical power, expected time to signal and expected sample size for group and continuous sequential analysis with Poisson data.
Performance.Threshold.Binomial	Statistical Performance and Alpha Spending For User-defined Signaling Threshold With Binomial Data.
Performance.Threshold.CondPoisson	Performance and alpha spending for user-defined signaling threshold for sequential analysis with conditional Poisson data.
Performance.Threshold.Poisson	Performance and alpha spending for user-defined signaling threshold for sequential analysis with Poisson data.
SampleSize.Binomial	Sample size calculation for continuous sequential analysis with binomial data.
SampleSize.CondPoisson	Sample size calculation for the continuous sequential CMaxSPRT for Poisson data with limited information from historical cohort.
SampleSize.Poisson	Sample size calculation for continuous sequential analysis with Poisson data.
Sequential	Analysis Support, Critical Values, Power, Time to Signal and Sample Size for Sequential Analysis with Poisson and Binomial Data.