CFO-Type Designs in Phase I Clinical Trials

Documentation for package ‘CFO’ version 1.1.1

aCFO.next	Determination of the dose level for next cohort in the accumulative calibration-free odds (aCFO) design
CFO.next	Determination of the dose level for next cohort in the calibration-free odds (CFO) design
CFO.oc	Generate operating characteristics of sigle-drug trials in multiple simulations
CFO.selectmtd	Select the maximum tolerated dose (MTD) for the real single-drug trial
CFO.simu	Conduct one simulation using the Calibration-free odds (CFO) or accumulative CFO (aCFO) design.
CFO2d.next	Determinate the dose level for the next cohort in the two-dimensional calibration-free odds (2dCFO) design.
CFO2d.oc	Generate operating characteristics of drug-combination trials in multiple simulations
CFO2d.selectmtd	Select the maximum tolerated dose (MTD) for the real drug combination trial
CFO2d.simu	Conduct one simulation using the two-dimensional calibration-free odds (2dCFO) design.
lateonset.next	Determination of the dose level for next cohort in the calibration-free odds type (CFO-type) design with late-onset toxicity
lateonset.simu	Conduct one simulation using the calibration-free odds type (CFO-type) design with late-onset toxicity.
plot.cfo	Plot the results by other functions
print.cfo	Generate descriptive summary for objects returned by other functions
summary.cfo	Generate descriptive summary for objects returned by other functions