Designing Multi-Arm Multi-Stage Studies

Documentation for package ‘MAMS’ version 2.0.0

MAMS-package	Designing Multi-Arm Multi-Stage Studies
MAMS	Designing Multi-Arm Multi-Stage Studies
mams	Function to design multi-arm multi-stage studies with normal endpoints
mams.sim	Simulating multi-arm multi-stage designs
MAMSNews	Shows changes and news
new.bounds	Function to update boundaries based on observed sample sizes
ordinal.mams	Function to design multi-arm multi-stage studies with ordinal or binary endpoints
plot.MAMS	Different generic functions for class MAMS.
plot.MAMS.stepdown	Different generic functions for class MAMS.
print.MAMS	Different generic functions for class MAMS.
print.MAMS.sim	Different generic functions for class MAMS.
print.MAMS.stepdown	Different generic functions for class MAMS.
stepdown.mams	Function to find stopping boundaries for a 2- or 3-stage (step-down) multiple-comparisons-with-control test.
stepdown.update	Update the stopping boundaries of multi-arm multi-stage study at an interim analysis, allowing for unplanned treatment selection and/or sample-size reassessment.
summary.MAMS	Different generic functions for class MAMS.
summary.MAMS.sim	Different generic functions for class MAMS.
summary.MAMS.stepdown	Different generic functions for class MAMS.
tite.mams	Function to design multi-arm multi-stage studies with time-to-event endpoints