# Mendelian Randomization Package

## Documentation for package ‘MendelianRandomization’ version 0.9.0

- DESCRIPTION file.
- User guides, package vignettes and other documentation.
- Package NEWS.

## Help Pages

calc.rho | Data on effect of calcium on fasting glucose (correlated variants)
calcium | Data on effect of calcium on fasting glucose (correlated variants)
calciumse | Data on effect of calcium on fasting glucose (correlated variants)
chdlodds | Data on lipid effects on coronary artery disease (uncorrelated variants)
chdloddsse | Data on lipid effects on coronary artery disease (uncorrelated variants)
cML_estimate | Estimate with Regular Likelihood
cML_estimate_random | Estimate with Regular Likelihood Using Multiple Random Start Points
cML_SdTheta | Standard Error of Estimated Theta
DIVW-class | DIVW Class
Egger-class | Egger Class
extract.pheno.csv | Extract summarized data from a PhenoScanner .csv file (legacy)
fastgluc | Data on effect of calcium on fasting glucose (correlated variants)
fastglucse | Data on effect of calcium on fasting glucose (correlated variants)
hdlc | Data on lipid effects on coronary artery disease (uncorrelated variants)
hdlcse | Data on lipid effects on coronary artery disease (uncorrelated variants)
invcov_mvmr | Generate the list of inverse of covariance matrices used in 'MVMR-cML-DP'
IVW-class | IVW Class
ldlc | Data on lipid effects on coronary artery disease (uncorrelated variants)
ldlcse | Data on lipid effects on coronary artery disease (uncorrelated variants)
lipid_eaf | Data on lipid effects on coronary artery disease (uncorrelated variants)
lipid_effect | Data on lipid effects on coronary artery disease (uncorrelated variants)
lipid_other | Data on lipid effects on coronary artery disease (uncorrelated variants)
MaxLik-class | MaxLik Class
MRAll-class | MRAll Class
MRcML-class | MRcML Class
MRConMix-class | MRConMix Class
MRHetPen-class | MRHetPen Class
MRInput-class | MRInput Class
MRLasso-class | MRLasso class
MRMBE-class | MRMBE Class
MRMVInput-class | MRMVInput Class
mr_allmethods | Mendelian randomization estimation using all methods
mr_allmethods-method | Mendelian randomization estimation using all methods
mr_cML | Constrained maximum likelihood (cML) method
mr_cML-method | Constrained maximum likelihood (cML) method
mr_conmix | Contamination mixture method
mr_conmix-method | Contamination mixture method
mr_divw | Debiased inverse-variance weighted method
mr_divw-method | Debiased inverse-variance weighted method
mr_egger | MR-Egger method
mr_egger-method | MR-Egger method
mr_forest | Draw a forest plot of causal estimates
mr_forest-method | Draw a forest plot of causal estimates
mr_funnel | Draw a funnel plot of variant-specific estimates
mr_funnel-method | Draw a funnel plot of variant-specific estimates
mr_hetpen | Heterogeneity-penalized method
mr_hetpen-method | Heterogeneity-penalized method
mr_input | Inputting and formatting data for use in causal estimation
mr_ivw | Inverse-variance weighted method
mr_ivw-method | Inverse-variance weighted method
mr_lasso | MR-Lasso method
mr_lasso-method | MR-Lasso method
mr_loo | Leave-one-out estimates
mr_loo-method | Leave-one-out estimates
mr_maxlik | Maximum-likelihood method
mr_maxlik-method | Maximum-likelihood method
mr_mbe | Mode-based method of Hartwig
mr_mbe-method | Mode-based method of Hartwig
mr_median | Median-based method
mr_median-method | Median-based method
mr_mvcML | Multivariable constrained maximum likelihood method
mr_mvcML-method | Multivariable constrained maximum likelihood method
mr_mvegger | Multivariable MR-Egger method
mr_mvegger-method | Multivariable MR-Egger method
mr_mvgmm | Multivariable generalized method of moments (GMM) method
mr_mvgmm-method | Multivariable generalized method of moments (GMM) method
mr_mvinput | Inputting and formatting data for use in causal estimation
mr_mvivw | Multivariable inverse-variance weighted method
mr_mvivw-method | Multivariable inverse-variance weighted method
mr_mvlasso | Multivariable MR-Lasso method
mr_mvlasso-method | Multivariable MR-Lasso method
mr_mvmedian | Multivariable median-based method
mr_mvmedian-method | Multivariable median-based method
mr_mvpcgmm | Multivariable principal components generalized method of moments (PC-GMM) method
mr_mvpcgmm-method | Multivariable principal components generalized method of moments (PC-GMM) method
mr_pcgmm | Univariable principal components generalized method of moments (PC-GMM) method
mr_pcgmm-method | Univariable principal components generalized method of moments (PC-GMM) method
mr_pivw | Penalized inverse-variance weighted method
mr_pivw-method | Penalized inverse-variance weighted method
mr_plot | Draw a scatter plot of the genetic associations and/or causal estimates
mr_plot-method | Draw a scatter plot of the genetic associations and/or causal estimates
MVcML_SdTheta | Standard error estimate for MVMR-cML-BIC
MVEgger-class | MVEgger Class
MVGMM-class | MVGMM Class
MVIVW-class | MVIVW Class
MVLasso-class | MRMVLasso class
MVMedian-class | MRMVMedian class
MVMRcML-class | MVMRcML Class
MVmr_cML | MVMRcML method with Data Perturbation
MVmr_cML_DP | MVMRcML method with Data Perturbation
MVPCGMM-class | MVPCGMM Class
PCGMM-class | PCGMM Class
phenoscanner | PhenoScanner
pheno_input | Extract summarized data from PhenoScanner
PIVW-class | PIVW Class
trig | Data on lipid effects on coronary artery disease (uncorrelated variants)
trigse | Data on lipid effects on coronary artery disease (uncorrelated variants)
WeightedMedian-class | WeightedMedian Class